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In today’s laboratory, accuracy and efficiency play an extremely important role. Traditional manual pipetting method has been greatly replaced by automatic digital pipette dispenser to improve precision, reproducibility and overall working efficiency. As national high-tech enterprise with 80 independent intellectual property rights (the number is still growing), Hangzhou Zhongwang Technology Co., Ltd. Fully understands profound impact of digital liquid handling on science research and Industrial testing.
Precision and Accuracy at Scale
Accuracy and precision of manually pipetted samples are susceptible to variation caused by operator differences, fatigue, or simple mistake. In fully digital pipette dispensing setup, robotic arms driven by motorized computer commands automate liquid handling. Best digital dispensers can dispense liquid within +/- error allowance set by ISO 8655-2. They have as low as -0.09% in systematic errors and less than 0.1% (coefficient of variation) or random errors in case of large volumes. This level of control is vital in research areas like qPCR, dose-response, and compound screening. Errors of just microliters in such an experiment could drastically impact results. Expanded Liquid Handling Capabilities Modern digital liquid dispensers have capacity from as low as 8 picoliters to 10 microliters, at high precision.
Some instruments provide finest dispense resolutions down to one thousandths, at which point, thousands of dispenses are delivered by highly precise stepping motors. Precision in this level is particularly important when dispenses are on high-value reagents or small sample volume. Reduced Cost Although initial cost can be significant for advanced equipment, in long-term it may become significantly more affordable to run. You avoid costly reagent wastage and fully automated workflow can often significantly increase output, thus contributing to lower experimental costs overall.
Enhanced Workflow Efficiency and Time Savings
Most obvious benefit of digital pipette dispensers is faster lab processing: Manual serial dilutions of each plate could take as long as 10 minutes for each plate whereas digital systems perform these tasks in approximately 15 seconds, which means more than 40-fold higher quantity. But even outside process of simple pipetting total savings add up. Automation simplifies experiment set up saving precious researchers' hours for data analysis and higher priority scientific work.
In case of typical high throughput screening experiment, same experiment performed using digital liquid handler, execution speed up can reach up to 77% compared to traditional manual work flow that includes various liquid handling operations.
Because modern digital pipetting systems offer simplified user interfaces with drag-and-drop controls and ready-made protocol library, which remove complexity and need for coding, automating processes can be done by any researcher regardless of her previous experience with automated solutions.
Reduction of Cross-Contamination and Waste
The largest risk to data integrity associated with pipetting is the potential for cross-contamination from the pipette tip. Digital non-contact dispensing systems utilize disposable pipette tips or cartridges that prevent sample carry-over, and sophisticated tip-exchange functionality where robotic arm, dispensing the liquid will automatically replace disposable pipette tip if needed during operation to avoid cross-contamination issues when transferring liquids. Reduced plastics waste Digital, ink-jet dispensing systems can often dispense directly to well within plate, eliminating the need for pipette tip, which reduces consumable expenditure and the amount of plastic waste. Smart, ultra low-dead volume (as little as 4.5 μL total dead volume per dispense channel) liquid dispensing machines also guarantee maximum utilization of expensive stock reagents, again minimizing consumable expenditure and waste.
Versatility and User Safety
Digital pipette dispenser: versatility for countless uses: The modern digital pipette dispenser is versatile for countless applications and liquids, even if your chemistries run from aqueous solutions and organic solvents to viscous fluids and those in DMSO solutions. With modern digital pipettes you can execute your drug combination study, enzyme profiling, biochemical assay, synthetic biology application, cell-based assay and much more without issues. Safety benefit In chemical and biochemical labs, one will often work with corrosive/toxic substances or solvents that will evaporate quickly.
Thanks to modern touchscreen dispenser the operators remain distanced from any risk of exposure to the substances to be dispensed: and thus work much safer,. Special systems are chemical resistant (even when working with, such as, 96 % sulfuric acid and organic solvents.
Summary
The electronic liquid dispenser is kind of groundbreaking technical product that is essential in the modern scientific laboratory, it is capable of accurately dispelling required volume of liquid with higher speeds, fewer contamination risks, more versatility, and even more safety as compared to manual pipetting equipment. It is increasingly important in any lab that wishes to ensure maximum result reproducibility, lower running costs and sped up testing process. We believe our technology could support all laboratory wishing to get an automatic lab solution that enable more consistent, and greater research results and achievements.